Navigating the tense, atmospheric corridors of the Raccoon City Police Department in the Resident Evil 2 Remake requires constant vigilance and efficient resource management. Throughout the game, players encounter various locked safes, dial combinations, and puzzle mechanisms designed to safeguard vital ammunition, inventory expansions, and weapon upgrades. Knowing these combinations in advance helps streamline your playthrough and ensures survival against relentless biological threats.

Police Station Dial Locks and Safe Combinations

In the West Office on the first floor, players can unlock two distinct dial locks on Leon or Claire's desk to gain early tactical upgrades. Entering NED on the left lock and MRG on the right lock opens the desk for extra handgun magazines or speed reloaders. Nearby, the safe in the same office opens with the combination Left 9, Right 15, Left 7 to yield a valuable Hip Pouch inventory upgrade.

Moving up to the upper floors, additional locks guard crucial supplies needed to survive tough encounters. The shower room locker on the second floor opens using the code CAP, while the hallway locker on the third floor uses the combination DCM. Opening these containers rewards players with essential shotgun shells or submachine gun ammo depending on the chosen scenario.

Sewer Area Lockers and Safe Solutions

As the story transitions into the murky underground sewer network, players face more intricate puzzle locks protecting high-tier items. In the Control Room, players can open the locker by entering the code SZF to secure additional ammunition. This area demands quick decision-making, so opening containers swiftly prevents unnecessary backtracking while evading enemies.

The safe located in the Treatment Pool Room requires a combination hidden on the side of the vault frame itself. Turning the dial Left 2, Right 12, Left 8 opens the safe to deliver a powerful weapon upgrade component. Equipping these attachments significantly enhances firepower and handling during intense boss encounters later in the campaign.

Statue Medallion Solutions and Greenhouse Codes

Unlocking the underground passage beneath the Main Hall requires collecting three distinct medallions scattered around the station. In Scenario A, the Lion Statue combination is Lion, Twig, Eagle, the Unicorn Statue requires Fish, Scorpion, Vase, and the Maiden Statue uses Woman, Bow, Snake. Scenario B alters these arrangements slightly, demanding altered sequences found within scattered operational notebooks.

In the NEST Laboratory facility, players must decipher abstract terminal symbols to access key areas and control systems. Entering the ladder control code on the Greenhouse control panel allows entry to the lower levels of the research facility. Additionally, entering the liquid drug synthesis code unlocks the mixing station to prepare the herbicide compound necessary for clearing plant obstacles.

Portable Safe Decryption Strategy

Portable safes are scattered across various locations, requiring players to solve a unique keypress sequence to open them. Each button lights up a green bulb on the circular display, and the goal is to press all eight buttons in counterclockwise or clockwise order without triggering a mistake. Because the exact button layout is randomized for every playthrough, taking a moment to map the sequence manually guarantees success without wasting precious time.

Successfully opening portable safes rewards players with spare keys needed for the Safety Deposit Room terminal. Replacing the missing keys allows access to inventory extensions and additional defensive items that drastically improve your odds of survival. Managing your item storage efficiently ensures you stay prepared for the final confrontations in Raccoon City.